Globalization Essay Example | Topics and Well Written Essays - 2000 words - 5

Globalization - Essay Example This business expansion facilitates exchange of technology and expertise so that developing economies can build upon the existing knowledge base. The business expansion creates new business opportunities through economies of scale so that the prices are reduced. This means that economies have more resources to spare in investing in living standards. Critical evaluation Globalization has enabled economies like China and India to join the world economy. By joining the World Trade Organization (WTO), the Chinese government has been able to attract massive amounts of foreign direct investments in its economy. Such success would not have been possible without infrastructure development. Because China has improved infrastructure, companies from the developed economies have established operations in the country. Given China’s massive population, foreign companies can access a very large market which leads to economies of scale. Another advantage of operating in China is that the labo ur costs are low, so that companies can reduce production costs to a significant extent. This enables them to offer goods and services at significantly lower prices in all parts of the world. This is the international trade which has been facilitated through the process of globalization. The process of globalization has been aided by technological developments. The emergence of the Internet has enabled businesses to coordinate their international operations to a greater extent. The enhanced coordination has also led to cost streamlining. Therefore multinational organizations have been able to create new business opportunities and capitalize upon them to the fullest extent. By creating additional business opportunities, the companies have been able to reduce the competitive threats in their respective industries. According to Porter’s five forces analysis, the competitive threat in an industry is defined by the threat of new entrants, the threat of substitute products, bargain ing powers of customers and suppliers and finally, the threat of existing competition (Scholte, 2005). Globalization affects all five forces. The threat of new entrants has been reduced since companies no longer have to be limited to the domestic markets. The threat of substitute products has been reduced because globalization enables companies to offer products and services in markets which previously did not have them. The bargaining power of customers is less of a threat because companies can achieve economies of scale more quickly, so that loss of customers from high prices does not affect profitability. Bargaining power of suppliers is also reduced as multinational companies can offer a lot of business opportunities to the supply chain management companies so that they are willing to offer lower prices. The threat of existing competition is reduced because there are international markets which offer additional demand. This means that for multinational companies, the competition has decreased. However for domestic companies, globalization has increased competition. For example, the domestic companies in developing economies are facing increased competition as multinational companies are entering their markets through globalization. Therefore, while multinational companies are creating new business opportunities through globaliz

Progressive Essay Topics on Health Care - Turning Health Care Into a National Issue

Progressive Essay Topics on Health Care - Turning Health Care Into a National Issue'Progressive'progressive' on the subject of health care and the government's role in it? Who needs any more, no? But that is not what the 'Left' has taught us. When they say, 'Provide health care to all', they are not saying that everyone must have health care, but that a free market system should be employed to provide it to those who want it.The progressive article is written by Tom Paine, a founding father of the United States. In his popular novel, Agrarian Justice, he wrote that the best way to provide for the health of citizens is to allow them to keep their own health-care plans, rather than forcing everyone to use the government-run health care programs. He also said that if there was enough money to get the job done, then he was for providing health care to all the citizens.There is nothing new in this, nor is there anything radical in these ideas. Many college students have been taught these things since they were young. It is only a matter of time before they are handed over to political circles to teach their curriculum. The key thing is that these ideas should be made plain and heard in political discourse.But then again, these ideas and other progressive writings are out of place in a political discourse between two political parties. The Republicans want to cut spending, and the Democrats are the ones who want to increase it. They find themselves on opposite sides of the fence, and so they argue.But there is a better solution. The solution would be for all people to become true representatives of their communities. So if your community has high levels of obesity, let's do something about it. But if the community is filled with obese people, and is not improving, then send someone to put on the word that it is unacceptable to put up with it.We can use the opportunity to learn how to make arguments in such a way that we can see the importance of health care. It is an opportunity to show how an argument should be made, and the necessity of the arguments that are made. It is also an opportunity to figure out whether or not those who are in charge of promoting health care are doing a good job.We can take advantage of the opportunity to make health care a national issue and see whether or not we can build strong grassroots work. If we make it a national issue, we can work together to change our national policy.

The Pain of College Papers on Borderline Personality Disorder

The Pain of College Papers on Borderline Personality Disorder The 5-Minute Rule for College Papers on Borderline Personality Disorder Let's look at a good example of a man attending college with BPD, and the particular problems that can arise. If nobody can understand, then there's no point in sharing the specifics of what goes on in the relationship. In the start, there's no way to find they are in reality building a bubble around both of you, isolating you from outside opinion and support. If you're able to learn how to identify when you're serving as a blood-bag, and find out how to stop, you're going to be taking away the support that rock stars and narcissists will need to survive. In the procedure for development, there are numerous failures in forming relationships. You're able to realize you're deserving of a true partner. You're permitted to terminate your relationship with toxic relatives. Individuals with BPD could possibly be equally as baffled as their family and friends by their failure to finish the school term. Clients have a tendency toward go to drastic measures like self-mutilation or other destructive behaviors to grab the therapist's interest. People with BPD often discover that it's challenging to regulate their emotions. The defects shouldn't be brought on by developmental, socio-cultural, drug, or health care aspects. College Papers on Borderline Personality Disorder: No Longer a Mystery The malignant type of borderline personality disorder is actually characteristic of this. Often dwelling in a state of denial, narcissists might also be suffering from mental health difficulties, besides their personality disorder. There are a lot of websites having border personality disorder test which will be able to help you determine whether somebody you care about could have the signs of BPD. People with borderline personality disorder may believe this abandonment implies they are bad. In essence the larger narc goes to therapy to enhance their tradecraft of con-artistry. It would be quite challenging to take care of a patient that doesn't wish to be in therapy or holds ill will for the man or woman attempting to treat them. The physician will also assess the patient to understand the present symptoms as bipolar will make the individual feel low or high. Based on the particular symptoms the patient has, medications might be prescribed. The patients should be encouraged to speak regarding their feelings. Your patient might have a three-day stay in the hospital and have five distinct nurses take care of those. Tell the assistant which you were referred by your physician and would love to establish an appointment for a mental health evaluation. You'll get a last appointment in which you sit with your psychologist and talk about the findings of the mental wellness evaluation. There might also be peer-led mental health meetups which you could attend. Most men and women opt not to. The most significant thing that happened was I started to trust myself. Save your hope for those things which you're building. Steer clear of those people. Anyway, important brain variations exist between women and men. Giving up your own feelings to support somebody else is the origin of being a blood-bag. In addition, it takes away the stress of needing to find someone by yourself. Relationships and the individual's emotions may sometimes be viewed by other people or characterized as being shallow. Generally speaking, it's the disturbance of self identity, image behavior and the general personality function. Physical boundaries aren't kept and emotional boundaries aren't respected. If a person is acting in a manner that fits a narcissistic pattern, you may use the ways of coping with narcissism to guard yourself, without feeling bad about potentially mislabeling the other person for a narcissist. Exclusively by understanding the main cause can you start the practice of healing. If some individuals have a couple of those traits then there's a great prognosis they can change. It's common for non-disordered folks to lessen their own expectations and attempt to normalize the behavior. A limit which you want to make with that hope. There are a few relationships where there's a switch dynamic, where there are people which take turns abusing one another. What You Should Do to Find Out About College Papers on Borderline Personality Disorder Before You're Left Behind Toxic (or Malignant) The Exhibitionist Narcissists, also known as Somatic, are people who always need to be the middle of attention. Students with borderline personality should also concentrate on developing a supportive living environment to be successful academically. Because the individual is taking action. That individual is showing you they don't wish to modify.

The Single Best Method to Use for Why Do College Students Have to Write Research Papers Uncovered

The Single Best Method to Use for Why Do College Students Have to Write Research Papers Uncovered What Is So Fascinating About Why Do College Students Have to Write Research Papers? If you're going to pay to obtain a customized research paper, then you will need value for money. Examine the web for more directions about how to custom write a fantastic essay. Quit procrastinating and place your very first order immediately to find the ideal offer and have your customized research papers done ASAP with no excess work. However, I have tried everything. Our site is the perfect spot for students of all ages, who want to acquire efficient and fast help with writing research or some other work. If writing a paper gets difficult for you, there are lots of choices to acquire reliable assistance. If you opt to select our research paper help, the very first thing you ought to do is begin placing the purchase. It's about many more than content. The Do's and Don'ts of Why Do College Students Have to Write Research Papers Students want to compare the info they've found to come across themes. They are not the only ones who hate homework. They often have to do a great deal of essay writing in college. They face the problem of college assignments overload every single day. With the latest development of academic resources online, there is not any excuse for teachers, parents, and students not taking full benefit of the chance to have an excellent time with exciting and appropriate homework assignments. If you're likely to let colleges set you under a heap of student loans, you need to at least try and get your money's worth from the education. There are a number of reasons that may make students hate writing their college assignments like the absence of the interest and capacity to compose competent and perfect college assignments. Their parents hate it as well. Don't forget that writing a great sociology paper starts with asking a superb sociological question. You are able to buy affordable essay on the internet website. Secondary sources articulate and describe somebody else's interpretation of an occasion. Writing is among the essential elements of communication which reaches the center of the reader, it doesn't just enhances the imagination and vocabulary but in addition triggers his thoughts in the subconscious mind of the reader. There's a standard, preferred approach to compose an original research paper. As an example, sometimes you have to do just a little bit of background research and reading before you are able to develop a research question. It's likewise not efficient to do too much research before you truly understand what you're searching for. Following that, speak with the professor about a few of your general thoughts and the potential research directions you're considering pursuing. In the last year of college, research paper topics need to be more specific and the research ought to be in-depth. When you purchase research papers via an unreliable. The very first year research paper has ever sent a mixed message. By way of example, our research paper writing service has a mixture of ex-professors, published authors. Why Do College Students Have to Write Research Papers - the Conspiracy We is acceptable as a means of avoiding passive voice. As soon as you pay to have a paper written, you set your academic destiny in the hands of somebody else. Then I really would need to be a stripper. How to Find Why Do College Students Have to Write Research Papers Online It appears to me that payment needs to be due up front and in full. What's more, we provide VIP support for students who desire to receive the service including all the benefits they could want. Why is it that you've got to pay more for the very same service if you could choose. This service exists for a number of reasons. Life After Why Do College Students Have to Write Research Papers If you wish to pay for essay writing to a well-educated expert and get an. All our writers have top-of-the-line education and can assist you, since we've got double superior check, and you won't ever receive a paper that embarrasses you. In our technological age, being requested to compose a complete essay can appear a little antiquated. The debut of your college essay lays the groundwork for the remainder of the essay. Buying a research paper sample for college submission is among the options. As you write your term papers, it'll be essential for you to. Writing college papers is significantly simpler if you're organized and understand the kind of paper you're writing. It is crucial to think about buying college papers online instead of doing it by yourself. Colleges would be irresponsible to provide you a place in their program if you don't have the fundamental skills needed to be successful. With the many pursuits that students have on their day-to-day schedules, it can be difficult to get the opportunity to all the requisite research and writing. Some students don't comply with the demands of the chosen citation style whilst preparing an assignment. Students who have not ever gone through a comprehensive revision process are accustomed to handing in and receiving poor grades on first drafts.

Family in Europe History Coursework Example | Topics and Well Written Essays - 1250 words - 3

Family in Europe History - Coursework Example In case a family was already on a high rung in a social ladder, a smart marriage arrangement could be highly advantageous through a thoughtful market strategy. As time passed over the centuries, there was a slow and gradual change towards more freedom of choice and a much greater acceptance of love as a basis for marriage. Parents had every say in the matter in choosing a partner as well as bargaining about the dowry. The general notion was that unless a person could afford to get married they should, otherwise it was not advisable. Though parents took trouble in working out a marriage for their children, the youngsters met their lovers in the fields, barns, at the fairs and even on pilgrimages. Most marriages took place between members of the same religion, nationality and caste. It is rather surprising to note that the word family did not mean blood relations or related by marriage, but the Latin word â€Å"famulus† referred to a domestic establishment’s live – in staff. Until the 19th century, Europeans did not do away with the meaning of family, but as the idea of kinship took shape, the meaning of â€Å"family† took on a whole new perspective while the old meaning has become obsolete in these modern times. In the past a household was not only the private residence of a family, but also a place for the public eye. Historians having worked on demographic data between the 16th and 19th centuries and have put to rest the common notion that people lived in very large households compared to the micro families of today. After much investigation, they have come to rest on the fact that families were of two kinds – small or average and large families. The small families in Europe had one or two children while the large families had about seven to ten members. However, when comparing the rural and urban households, they found that most of the people in the urban areas preferred to have small families comprising of one or two

MicroRNA-21 Concentrations in Breast Cancer

MicroRNA-21 Concentrations in Breast Cancer Direct Serum Assay for MicroRNA-21 Concentrations in Early and Advanced Breast Cancer Abstract Background Small noncoding RNA molecules known as microRNAs (miRs) are involved in the regulation of gene expression. The hypothesis was based on the biomarker, miR-21 present in the serum, which related to the presence and stage of breast cancer. The direct application of reverse-transcription quantitative real-time PCR (RT-qPCR) in a direct serum assay has been used for the quantification and detection of the miR-21 in breast cancer patients. Methods A total of 102 breast cancer patients with varying stages of breast cancer and 20 healthy female patients were tested by the RT-qPCR applied directly in serum assay for miR-21. Results Detection for RT-qPCR-DS was limited to 0.625 µl of serum. miR-21 levels detected in the healthy donors were comparatively lower with respect to breast cancer patients with different stage of the disease. A significantly higher levels of miR-21 was detected in patients with stage IV breast cancer compared to patients with other stages of the disease. The odds ratio was 1.796 and area under the curve was 0.721 for the distinction of loco regional breast cancers and healthy donors. Multivariate analysis confirmed that a correlation of miR-21 concentrations and stage of breast cancer existed. Conclusion- The novel RT-qPCR-DS serves as a better technique in detecting circulating miR. miR-21 proves to be a significant biomarker for breast cancer, which could also probably detect the progression of the disease. Further research could lead to improved breast cancer care by this serum biomarker as a key tool. EVALUATION Traditional methods Mammography (also known as film mammography) is a traditional method for screening breast cancer (Boyd et al., 2007). Its principle lies in the use of low-dose x-rays. Soft tissue such as fat is radiographically lucent, which appears dark on a mammogram. In contrast, stroma and epithelial tissue are radiographically dense, which is termed mammographic density, appearing light on a mammogram (Boyd et al., 2007). It has been established that the more immense the density, the more association it had with regard to the greater risk of breast cancer. A dense tissue present in 75% or more of the breast poses a risk of breast cancer (Boyd et al., 2007).   A limitation of this method revolves around the fact that expansive mammographic density may be difficult to detect by mammography, thereby indicating a false negative (Boyd et al., 2007). Cancers may be masked by surrounding dense breast tissue, limiting the sensitivity of the screening (Boyd et al., 2007), thereby increasing the risk o f breast cancer (Pisano et al., 2005). High false positive results and costs are drawbacks of mammography (Asaga et al., 2010).   An alternative breast cancer screening technique is the MRI, which is sensitive, but its limitations include the lack of cost-effectiveness and specificity (Esserman et al., 2007). Digital mammography, an upgrade to film mammography allowed the manipulation of the degree of contrast on digital images. This allowed the differentiation of dense breast tissues from malignant cells (Pisano et al., 2005). Women under 50 years of age, with dense breast tissue or those who are pre-menopausal or peri-menopausal were mostly detected by digital mammography (Pisano et al., 2005). In comparison to the film mammography method, digital mammography has an increased cost (1.5-4 times more), but is quicker at developing the image (Pisano et al., 2005). BRCA1 and BRCA2 are tumour markers used to identify individuals who are at risk of developing breast cancer via inheritance (Duffy, 2001). Only 5-10% cases of breast cancers are hereditary. 80-85% risk of developing breast cancer was reported in individuals carrying either the BRCA1 or BRCA2 gene (Duffy, 2001). Cancer antigen 15-3 (CA 15-3) is a gene product of the MUC1 gene. Overexpression of MUC1 gene in malignant breast tumours allows CA 15-3 to be used as a tumour marker for breast cancer (Kabel, 2017). False positive results were reported in benign breast and benign liver diseases (Kabel, 2017). The serum concentration of patients with elevated levels of CA 15-3 became more detectable as the size of tumour and severity of the disease increased. Therefore, this is suitable as a prognostic and pharmacokinetic biomarker (Kabel, 2017). The lack of sensitivity for women with early disease have been a main limitation of CA 15-3 biomarker (Duffy et al., 2010). Rising levels of another extensively used biomarker, carcinoembryonic antigen (CEA) indicated poor treatment or the risk of recurrence following treatment (Kabel, 2017). The lack of disease sensitivity and specificity prevents the use of CEA as predictive biomarker (Kabel, 2017). Estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (HER-2) serve as pharmacokinetic biomarkers (Kabel, 2017). Relevance to current article Elevated levels of miR-21 was observed in breast cancer patients (N = 102) compared to healthy females (N = 20) in the study done by Asaga et al., (2010). Detection of circulating miR by RT-qPCR-DS was robust and effective (Asaga et al., 2010). The differentiation of patients with stage I, stage II or stage III from patients with stage IV breast cancer was possible with the direct assay, but not by the standard RT-qPCR (Asaga et al., 2010). The assay had a sensitivity and specificity of 67% and 75% respectively in distinguishing loco regional breast cancer patients from healthy patients. The specificity and sensitivity in distinguishing patients with stage IV breast cancer from the earlier stages was 86% and 70% respectively (Asaga et al., 2010). The use of the novel RT-qPCR in direct serum assay reduced mechanical and human errors and minimized the time and overall cost (Asaga et al., 2010). CA 15-3 and CEA are low in sensitivity and specificity, therefore cannot be used as a diagnostic marker (Ng et al., 2013). Comparatively, miR-21 shows a better specificity and sensitivity (Asaga et al., 2010). Current methods 3D mammography is an evolution of the mammography technology (Houssami et al., 2017). 3D mammography improves cancer visibility by reducing the images of overlapping breast tissue, leading to the visualization of benign and malignant breast lesions which would have been masked in traditional mammography (Houssami et al., 2016). It may also decrease the false positive recall. Cost and time-taken to read a 3D mammography are limitations of this method (Houssami et al., 2017). A study by Ng et al., (2013) detected elevation in miR-451, miR-16 and miR-21, while a reduction in miR-145 was observed in the plasma of breast cancer patients. The combination of miR-451 and miR-145 served as the best biomarkers for breast cancer with an optimal specificity of 92% and optimal sensitivity of 90% in distinguishing breast cancer patients from control subjects of other types of cancers (gastric cancer, lung cancer) recruited in the study (Ng et al., 2013). This study by Ng et al., (2013) recognized a combination of miRNAs specific to breast cancer and not the other cancers. Drawbacks include the lack of information regarding whether these miRNAs can be used to distinguish between the subtypes of breast cancer and between sporadic and familial forms (Ng et al., 2013). The study done by Asaga et al., (2010) only focused on miR-21 as a predictive marker in breast cancer, but miR-21 has been implicated in other types of cancer too. Comparatively the study done by Ng et al. , (2013) has identified biomarkers specific to breast cancer. In conclusion, the use of miR-21 as a biomarker in breast cancer presented a correlation of circulating miR-21 with the stage of breast cancer. More research is required to establish miR-21 as an important biomarker in breast cancer (Asaga et al., 2010). A combined expression analysis of miR-21 and miR-191 increased the specificity to 100% and sensitivity to 92% (Chen and Wang, 2013). The study done by Chen and Wang (2013) proved that a combination of miRNAs were better as a predictive biomarker for breast cancer. WORD COUNT ABSTRACT 243 EVALUATION 1039 REFERENCES Asaga, S., Kuo, C., Nguyen, T., Terpenning, M., Giuliano, A. and Hoon, D. (2010). Direct Serum Assay for MicroRNA-21 Concentrations in Early and Advanced Breast Cancer. Clinical Chemistry, 57(1), pp.84-91.Boyd, N., Guo, H., Martin, L., Sun, L., Stone, J., Fishell, E., Jong, R., Hislop, G., Chiarelli, A., Minkin, S. and Yaffe, M. (2007). Mammographic Density and the Risk and Detection of Breast Cancer. The New England Journal of Medicine, 356(3), pp.227-236. Chen, J. and Wang, X. (2013). MicroRNA-21 in breast cancer: diagnostic and prognostic potential. Clinical and Translational Oncology, 16(3), pp.225-233. Duffy, M. (2001). Biochemical markers in breast cancer: which ones are clinically useful?. Clinical Biochemistry, 34(5), pp.347-352. Duffy, M., Evoy, D. and McDermott, E. (2010). CA 15-3: Uses and limitation as a biomarker for breast cancer. Clinica Chimica Acta, 411(23-24), pp.1869-1874. Esserman, L., Shieh, Y., Park, J. and Ozanne, E. (2007). A role for biomarkers in the screening and diagnosis of breast cancer in younger women. Expert Review of Molecular Diagnostics, 7(5), pp.533-544. Houssami, N., Là ¥ng, K., Bernardi, D., Tagliafico, A., Zackrisson, S. and Skaane, P. (2016). Digital breast tomosynthesis (3D-mammography) screening: A pictorial review of screen-detected cancers and false recalls attributed to tomosynthesis in prospective screening trials. The Breast, 26, pp.119-134. Houssami, N., Bernardi, D., Pellegrini, M., Valentini, M., Fantà ², C., Ostillio, L., Tuttobene, P., Luparia, A. and Macaskill, P. (2017). Breast cancer detection using single-reading of breast tomosynthesis (3D-mammography) compared to double-reading of 2D-mammography: Evidence from a population-based trial. Cancer Epidemiology, 47, pp.94-99. Kabel, A. (2017). Tumor markers of breast cancer: New prospectives. Journal of Oncological Sciences. Ng, E., Li, R., Shin, V., Jin, H., Leung, C., Ma, E., Pang, R., Chua, D., Chu, K., Law, W., Law, S., Poon, R. and Kwong, A. (2013). Circulating microRNAs as Specific Biomarkers for Breast Cancer Detection. PLoS ONE, 8(1), p.e53141. Pisano, E., Gatsonis, C., Hendrick, E., Yaffe, M., Baum, J., Acharyya, S., Conant, E., Fajardo, L., Bassett, L., DOrsi, C., Jong, R. and Rebner, M. (2005). Diagnostic Performance of Digital versus Film Mammography for Breast-Cancer Screening. New England Journal of Medicine, 353(17), pp.1773-1783.

Ecosystemic Psychology Essay

Ecosystemic Psychology – Definitions Definition Epistemology Epistemology is â€Å"the study of the origin, nature and methods, as well as the limits, of knowledge; it is also how things can be known, thus a framework for describing and conceptualizing what is being observed and experienced and it also specifies the nature of the relationship between the researcher (knower) and what can be known† (Terre Blanche & Durrheim, 2006, p. 6; Terre Blanche, Durrheim & Painter, 2006, p. 559; Goldenberg & Goldenberg, 2004, p. 507). Theory is â€Å"a general principle or a collection of interrelated general principles that is put forward as an explanation of a set of known facts and empirical findings† (Reber, 1985). Example If for example the researcher needs to rely on people’s subjective experiences of day to day living in an old age home, the researcher could adopt an interactional epistemological stance and make use of interviewing as a method of enquiry. This is reflective of the interpretive approach, â€Å"which aims to explain the subjective reasons and meanings that lie behind social action† (Terre Blanche & Durrheim, 2006, p. 7). Thus, epistemologically the observer needs to be empathetic and subjective in his/her approach. Theory The theory of psychosocial development by Erikson (1963) â€Å"holds that psychosexual growth and psychosocial growth take place together and that at each stage of life we face the task of establishing equilibrium between ourselves and our social world† (cited in Corey, 2009, p. 66). For example, very early in life the infant learns to trust or mistrust. If a baby has a careless parent, that does not meet the babies basic needs the baby can easily develop mistrust. Model A model is â€Å"an ideal, a standard, an example set up as worthy of imitation or copying† (Reber, 1985). Bandura’s social learning theory is well known in the discipline of psychology. Bandura did an experiment with a ‘Bobo Doll’ in which he used a live model of observational learning where children observed adults acting violently toward the doll. In the end the children imitated similar behaviour toward the Bobo Doll (http://psychology.about.com/od/ developmentalpsychology/a/sociall earning.htm). Technique A technique is â€Å"a fairly specific, learned procedure or set of procedures for accomplishing some specific goal† (Reber, 1985). Systematic sampling is an example of a technique. In systematic sampling a â€Å"fixed distance between elements is calculated† (Durrheim & Painter, 2006, p. 135). For example 100 out of a sampling frame of 1000, the interval will be calculated as follow: 1000/100 = 10. Thus every 10th element will be selected until there is a sample of 100.